Click
on thumbnails to see full sized pictures.Gastrointestinal Pathology- Clinicopathologic Correlation in Mucosal Biopsy
Case #5 (question #7 and #8):
A 50 year-old man with 5 mm subepithelial lesion along the greater curvature of stomach. Representative images are illustrated below:
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Question No. 7. The Answer is: (C) Fundic gland polyp.
Discussion: This is a fundic gland polyp. Note features of cystically dilated gastric fundic glands lined by normal-appearing chief and parietal cells or gastric surface epithelial cells.
Question No. 8. The Answer is: (B) False.
Discussion: Fundic gland polyps most often occur sporadically, although they are also common among patients with FAP. Of note, dysplasia may be present in up to 42% of FAP-associated fundic gland polyps, while dysplasia is found in less than 1% of sporadic fundic gland polyps.