Gynecologic Pathology- Pap Smear I

Question No. 10. The Answer is: (D)  Macronucleoli.

Discussion: Squamous cell carcinoma (SQC) is the most common malignant tumor of the cervix. Histologically and cytologically, SQCs range from well-differentiated keratinizing tumors to poorly differentiated, non-keratinizing tumors. The cells of non-keratinizing SQC tend to form 3-D groups with prominent nucleoli. Tumor diathesis is readily seen, especially on conventional smears. The nuclear area is not necessarily greater than dysplastic cells.

Comment