Gynecologic Pathology- Pap Smear I


Question No. 11. The Answer is: (C) Cellular pleomorphism.

 

Discussion: Squamous cell carcinoma (SQC) is the most common malignant tumor of the cervix. Histologically and cytologically, SQCs range from well-differentiated keratinizing tumors to poorly differentiated. The cells of keratinizing SQC are often in bizarre shape . Some are long and spindle-shaped, with small condensed nuclei (fiber cells). Others have a larger cytoplasmic body with a long tail (tadpole cells). Tumor diathesis is usually seen in non-keratinizing SQC.


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