Gestational Trophoblastic Disease

Question No. 7. The Answer is: (C) Only 2 and 4 are true.

Discussion: Hyperrectio lutenalis or multiple luteinized follicle ovarian cysts can result from increased levels of FSH, hCG, and clomiphene. Because of the role of hCG in the pathogenesis, twin pregnancies, molar pregnancies, and choriocarcinoma, which cause an increase in hCG, can all be associated with hyperrectio luteinalis. It is relatively reare in uncomplicated single pregnancies. hCG levels are generally higher in the first trimester, with a leveling off occurring in the latter two. For this reason, hyperrectio luteinalis can occur at any time during the pregnancy. It can also be due to an hypersensitivity to hCG. Major complications include hemorrhage, ascites, and hydrothorax can occur in severe cases. 

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