Gestational Trophoblastic Disease

Question No. 13. The Answer is: (D) Cytokeratin 5,6.

Discussion: hPL, beta hCG, PLAP and CD146 are all demonstrated in trophoblastic tissue. While low molecular weight cytokeratins such as CK 18 may be positive in certain GTD entities, CK 5,6 is unlikely to be of any differential value.

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