Central Nervous System- Basic Neuropathology

Question No. 11. The Answer is: (D)-  Herpes simplex encephalitis.

Discussion: Klüver-Bucy syndrome is an uncommon neurological syndrome. Clinical manifestations include An absence of emotional responses so that fear, rage, and aggression cease to exist; a compulsion to be overly attentive to all sensory stimuli, to examine all objects visually, tactilely, and orally; hypersexuality; psychic blindness or visual agnosia, in which objects are not recognized visually; and other manifestations such as memory loss, distractibility, seizures, and dementia. Klüver-Bucy syndrome is associated with bilateral damage in the amygdala and the adjacent temporal lobe. This pattern of damage can occur in, but not limited to, herpes simplex encephalitis, trauma and, sometimes, in Pick’s disease.

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