Central Nervous System- Basic Neuropathology
Question No. 16. The Answer is: (A)- Hypoxic ischemic changes of neurons.
Discussion:
This picture shows features of hypoxic/ischemic changes of neurons. The neurons have smudged and pyknotic nuclei, collapsed and flame-shaped eosinophilic cytoplasm with accentuated (artificial) pericellular space. This type of neuronal death characteristically seen in adults and older infants or children. In contrast, apoptotic cell death caused by hypoxic/ischemic injury is seen most commonly in premature infants and, less commonly, term neonates.