Department of Pathology, University of Oklahoma Health Sciences Center

 

December 2003, Case 306-1. Quiz set! Click here to see.

A 28 year-old Woman with Headache and Visual Disturbance

Clinical information: The patient was a 28 year-old woman who presented with headache and visual disturbance. A CT scan performed in an outside institute revealed a pituitary mass that enlarged the sella and compressing the optic chiasma. The patien was afebrile and not pregnant. The serum prolactin level is mildly elevated to about two times normal value. There was no history of compromised immunity or significant problem in the paranasal sinus. A surgery was performed. The following photographs are taken from representative areas of the surgical sample.

Com312-1-SQ1.gif (134649 bytes) Com312-1-FR-LM.gif (144198 bytes) Com312-1-FR-HM.gif (134906 bytes) Com312-1-LM.gif (161126 bytes) Com312-1-HM.gif (140067 bytes)Click thumbnails to see pictures.

Panel A is an intraoperative cytologic preparation. Panel B and C are low- and high-magnification of intraoperative frozen section respectively. Panel D and E low- and high-magnification of formalin fixed paraffin embedded sections respectively. 

What is your diagnosis? Discussion

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