Department of Pathology, University of Oklahoma Health Sciences Center
Anatomic Pathology Teaching Cases- List by Presentation & Diagnosis
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Bone and Joint |
| Case No. | Title | Diagnosis |
| Case 401-1 | A 33 year-old man with an epidural mass in thoracic spine | Myeloid Sarcoma |
| Case 402-2 | A 13 year-old girl with a mass in temporal bone | Langerhans' cell histiocytosis |
| Case 304-2 | A 25 year-old woman with vertebral/paravertebral mass of the thoracic spine. | Blastomycosis involving the spine with compression fracture and compression of the spinal cord. |
| Case P-02 | A 29 year-old woman with a skull mass for two months. | Langerhans' cell histiocytosis |
| Case P-03 | A 15 year-old female with progressive myelopathy. | Ewing's sarcoma/primitive neuroectodermal tumor (PNET) |
| Case 603-2 | A 11 year-old boy with a left tibial mass. | Adamantinoma, classic type, with pathologic fracture |
| Case No. | Title | Diagnosis |
| Case 310-2 | A A 65 year-old woman with red nodules on her breast. | Angiosarcoma of the breast associated with radiatin therapy |
| Case 406-2 | A 50 year-old woman with a breast mass. | Inflammatory myofibroblastic tumor (pseudotumor). |
| Case No. | Title | Diagnosis |
| Case 311-2 | A 35 year-old Chinese man with multiple nodules in the neck. | Kimura's disease. |
|
Gastrointestinal Tract |
| Case No. | Title |
Diagnosis |
| Case 404-3 | A 2 month-old infant with malrotation. | Granular degeneration of smooth muscle of vermiform appendix. |
| Case 505-2 | A 44 year-old woman with abdominal pain. | Histoplasmosis (in an HIV seropositive patient). |
| Case 602-1 | A premature neonate (30 weeks of gestation) with feeding problem and abdominal distension. | Necrotizing enterocolitis. |
| Case 602-2 | A 54 year-old man with a colonic mass and blood in stool. | Amyloidoma. |
| Case 711-1 | A 39 year-old HIV positive man with diarrhea. | Cryptosporidiosis. |
|
Urinary System |
| Case No. | Title | Diagnosis |
| Case 305-1 | A 42 year old man with microscopic hematuria. |
Polypoid
cystitis cystica et glandularis, intestinal type. |
| Case 410-2 | A 55 year-old man with hematuria. | Adenocarcinoma in situ of the urinary bladder. |
| Case 603-1 | A 63 year-old woman with diffuse abdominal pain, sharp left upper back pain and a solid mass in the kidney. | Mucinous tubular and spindle cell carcinoma. |
| Case 709-1 | A 63 year-old man with bilateral renal masses. | Papillary (chromophil) renal cell carcinoma |
|
Male Genital System |
| Case No. | Title | Diagnosis |
| Case 305-3 | A 32 year-old man with primary infertility. | Sertoli cell-only syndrome (germinal cell aplasia), mature (adult) variant. |
| Case 308-2 | A 49 year-old man with a scrotal mass. | Angiomyofibroblastoma of the scrotum. |
| Case 601-2 | A 22 year-old man with metastatic mature testicular teratoma in lymph node. | High-grade prostatic intraepithelial neoplasm (PIN) in metastasizing mature teratoma. |
|
Female Genital System (Gynecopathology) |
| Case No. | Title | Diagnosis |
| Case 710-1 | A 30 year-old woman with bilateral tubal ligation. | Adenomatoid tumor of fallopian tube. |
|
Head and Neck |
| Case No. | Title | Diagnosis |
| Case 304-1 | A 55 year-old man with rapidly enlarging thyroid mass. | Columnar cell variant of papillary carcinoma (columnar cell carcinoma) of thyroid. |
| Case 304-3 | A 45 year-old man with a mass in left submandibular gland. | Adenoid cystic carcinoma, low-grade, of the submandibular gland. |
| Case 309-3 | A 50 year old man with a rapidly enlarging parotid mass. | Salivary duct carcinoma ex pleomorphic adenoma. |
| Case 604-2 | A 54 year-old man with bilateral enlargement of submandibular glands and proteinuria. | Amyloidosis of salivary gland. |
| Case 704-1 | A 59 year-old man with a maxillary mass. | Malignant melanoma of the maxillary sinus. |
|
Hematopoietic System |
| Case No. | Title | Diagnosis |
| Case 401-1 | A 33 year-old man with an epidural mass in thoracic spine | Myeloid sarcoma |
| Case 402-2 | A 13 year-old girl with a mass in temporal bone | Langerhans' cell histiocytosis |
| Case P-02 | A 29 year-old woman with a skull mass for two months. | Langerhans' cell histiocytosis |
| Case 604-2 | A 54 year-old man with bilateral enlargement of submandibular glands and proteinuria. | Amyloidosis of salivary gland |
| Case 509-1 | A 73 year-old man with an itchy skin rash, hepatosplenomegaly, and increased in level of histamine in urine. | Aggressive systemic mastocytosis. |
| Case No. | Title | Diagnosis |
| Case 309-1 | A 55 year-old woman with a mass in the lung. | Sclerosing hemangioma. |
| Case 310-3 | A 18 year-old man with a mediastinal mass. | Yolk sac tumor (endodermal sinus tumor) of the mediastinum. |
| Case 312-2 | A 17 year-old boy with history of hemoptysis | Carcinoid. (well-differentiated neuroendocrine carcinoma) |
| Case 702-1 |
A 60 year-old, asymptomatic man with multiple nodules in the lung and mediastinal lymphadenopathy. |
Langerhans histiocytosis of the lung. |
| Case No. | Title | Diagnosis |
| Case 306-2 | A 21 year-old man with an asymptomatic mandibular mass. | Myxoma of the mandible. |
| Case 402-1 | A 9 month-old girl with a mass in the hard palate | Melanotic neuroectodermal tumor of infancy (retinal anlage tumor, melanotic progonoma). |
| A 23 year-old man with a mandibular mass. | Osteosarcoma, chondroblastic type, low-grade. | |
| Case 610-2 | An 8 year-old girl with macroglossia. | Plexiform neurofibroma of the tongue in a patient with neurofibromatosis 1 (NF1). |
| Case 712-1 | A 6 year-old boy with a mandibular expansion. | Ameloblastic fibroma. |
| Case No. | Title | Diagnosis |
| Case P-01 | A 70 year-old man with rigidity, decreased ocular movements, and dementia. | Progress suprnuclear palsy (PSP) |
| Case 308-1 | A 54 year-old man with acute onset pain, delusion, and rapid deterioration. | Rabies |
| Case 501-1 | A 10 year-old boy with history of asthma and lower extremity weakness. | Eosinophilic myelitis |
| Case 504-1 | An unresponsive 55 year-old woman. | Acute hemorrhage in basal ganglia following circulatory arrest. |
| Case 511-1 | A 10 year-old boy with headache, rapid neurologic deterioration, leptomeningeal and parenchymal enhancement. | Acute primary amebic meningoencephalitis with Naegleria fowleri. |
| Case 601-1 | A 42 year-old woman with difficulties in walking, confusion, multiple white matter lesions and history of substance abuse. | Leukoencephalopathy with vacuolar changes, compatible with cocaine induced vacuolar leukoencephalopathy. |
| Case 802-1 | A 41 year-old man with headache, altered mental status, and large intraventricular hemorrhage. | Moyamoya disease associated with massive intraventricular hemorrhage. |
| Case No. | Title | Diagnosis |
| Sim01 | A 60 year-old man with lower limb weakness, pain, and numbness. | Amyloid neuropathy. |
| Sim06 | A full term neonate with severe hypotonia. | X-linked myotubular myopathy |
| Case 305-2 | A 5 year-old girl with muscle weakness and pain. | Central core disease |
| Case 310-1 | A 56 year-old woman with rash and generalized weakness. | Dermatomyositis |
| Case 401-3 | A 56 year-old man with muscle pain and progressive muscle weakness | Adenylate deaminase deficiency |
| Case 404-1 | A 52 year-old man with muscle weakness | Central nuclear myopathy |
| Case 410-1 | A 76 year-old man with weakness in arms and hands. | Desmin related myopathy |
| Case 411-1 | A 23 year-old woman with elevated serum creatine kinase level and muscle weakness. | Glycogenosis type V (McArdle's disease) |
| Case 506-1 | A 54 year-old man with fatigue, muscle pain, and elevated creatine kinase. | Tubular aggregate myopathy. |
| Case No. | Title | Diagnosis |
| Case P-02 | A 29 year-old woman with a skull mass for two months. | Langerhans' cell histiocytosis |
| Case P-03 | A 15-year-old female with progressive myelopathy. | Ewing's sarcoma/primitive neuroectodermal tumor (PNET) |
| Sim02 | A 21 year-old woman who rapidly becomes quadriplegic. | Ependymoma |
| Sim03 | A 10 year-old girl with a hemispheric mass and hydrocephalus. | Papillary ependymoma. |
| Case 304-2 | A 25 year-old woman with vertebral/paravertebral mass of the thoracic spine. | Blastomycosis involving the spine with compression fracture and compression of the spinal cord. |
| Case 306-1 | A 45 year-old woman with an enhancing brain mass. | Chordoid meningioma |
| Case 307-1 | A 32 year-old woman with a ventricular tumor. | Central neurocytoma |
| Case 309-2 | A 5 year-old boy with a cystic lesion in the filum terminale. | Enterogeneous cyst of the spinal cord. |
| Case 311-1 | A 55 year-old man with an enhancing parietal mass. | Glioblastoma |
| Case 402-2 | A 13 year-old girl with a mass in temporal bone | Langerhans' cell histiocytosis |
| Com 403-2 | A large cerebellar mass | Atypical teratoid/ rhabdoid tumor (AT/RT) |
| Case 404-2 | A 18 year-old man with headache, ataxia, and cerebellar mass | Blastomycosis encephalitis |
| Case 401-1 | A 33 year-old man with an epidural mass in thoracic spine | Myeloid sarcoma |
| Case 401-2 | A 5 year-old boy with nausea and vomiting for 3 months | Pilocytic astrocytoma |
| Case 405-1 | A 54 year old woman with headache and vomiting | Secretory meningioma |
| Case 406-1 | A 5 year-old boy with a superficially located, partially cystic hemispheric mass. | Desmoplastic Infantile Ganglioglioma (DIG) with melanocytic colonization |
| Case 407-1 | A 64 year-old man with an intradural extramedullary spinal mass. | Hemangioblastoma |
| Case 407-2 | A 27 year-old man with headache, right side visual field loss, and weakness. | Inflammatory demyelinating pseudotumor |
| Case 408-2 | A 55 year-old woman with granulomatous dermatitis and cerebral masses. | Non-Hodgkin's lymphoma, large B-cell type, with extensive granulomatous inflammation |
| Case 409-1 | A 13 year-old boy with three years history of seizure. | Meningioangiomatosis |
| Case 409-2 | A 4 year-old girl with rapidly expanding cervical intradural, extramedullary mass. | Undifferentiated sarcoma. |
| Case 411-4 | A 48 year-old man with a midline cerebellar mass. | Cerebellar central liponeurocytoma |
| Case 411-3 | A 40 year-old man with back pain and a sacral mass. | Myxopapillary ependymoma |
| Case 412-1 | A 12 year-old girl with an enlarged optic nerve. | Pilocytic astrocytoma of the optic nerve (Optic nerve glioma) |
| Case 501-2 | A 65 year-old woman with an intraventricular mass. | Subependymoma |
| Case 502-1 | A 28 year-old woman with an intraventricular mass. | Choroid plexus papilloma with brain invasion. |
| Case 503-1 | An 18 month-old girl with a hypothalamic mass. | Pilomyxoid astrocytoma |
| Case 505-1 | A 28 year-old woman with a pineal mass. | Pineal germinoma with extensive granulomatous changes. |
| Case 507-2 | An infant born after 30 weeks of gestation and with a rapidly enlarging head. | Congenital craniopharyngioma with severe secondary hydrocephalus. |
| Case 512-1 | A 70 year-old man with confusion and neurologic deterioration after a minor fall. | Acute hemorrhage secondary to cerebral amyloid angiopathy. |
| Case 604-1 | A 5 year-old boy with headache, vomiting, ataxia and a pineal mass. | Primary mature teratoma of the pineal with growing teratoma syndrome and chemotherapy induced atypia |
| A 75 year-old man with progressive weakness and multiple lesions in the brain. | Primary T-cell lymphoma of the brain | |
| Case 606-1 | A 10 year-old girl with a cerebral hemispheric mass and headache. | Papillary ependymoma |
| Case 611-1 | An 8 year-old boy with headache and a mass in the posterior fossa. | Large cell (anaplastic) medulloblastoma, WHO grade IV. |
| Case 706-1 | A 67 year-old woman with a cerebellar and parietal enhancing lesions. | Diffuse large B-cell lymphoma. |
| Case 708-1 | A 30 year-old man with prolonged history of headache and a cerebellar hemispheric mass. | Dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease) |
| Case 705-1 | A 45 year-old woman with new onset seizure and an enhancing mass. | Sinus histioicytosis with massive lymphadenopathy (Rosai-Dorfman disease). |
| Case 707-1 | A 52 year-old man with history of endocarditis, stroke, and new enhancing lesion in temporal lobe. | Glioblastoma with extensive granular cell component (granular cell glioblastoma), WHO grade IV. |
| Case 801-1 | A rapidly expanding mass in the posterior fossa of a 4 year-old girl. | Anaplastic/large cell medulloblastoma, WHO grade IV. |
|
Pituitary, Sellar and Perisellar |
| Case No. | Title | Diagnosis |
| Case 312-1 | A 28 year-old woman with headache and visual disturbance | Lymphocytic hypophysitis |
| Case 403-1 | A 45 year-old woman with a sellar mass | Rathke's cleft cyst |
| Case 510-1 | A 60 year-old man with a pituitary mass. | Pituitary oncocytoma (null cell adenoma with extensive oncocytic changes). |
| Sim04 | A 20 year-old man with a sellar-suprasellar mass and sudden loss of vision. | Infarcted pituitary adenoma |
| Case No. | Title | Diagnosis |
| Case 411-2 | A 2 year-old girl with a funny looking eye. | Retinoblastoma |
|
Soft Tissue |
| Case No. | Title | Diagnosis |
| Case 306-3 | A 29 year-old woman with a mass in her thigh. | Mesenchymal chondrosarcoma |
| Case 307-2 | A 48 year-old woman with a mass in her thigh. | Cellular Myxoma (Low-grade myxoid neoplasm with recurrent potential) |
| Case 308-2 | A 49 year-old man with a scrotal mass. | Angiomyofibroblastoma of the scrotum |
| Case 607-1 | A 6 month girl with a mass in her right arm. | Fibrous hamartoma of infancy |