Department of Pathology, University of Oklahoma Health Sciences Center
November 2004, Case 411-4.
A 48 year-old man with a midline cerebellar mass.
Clinical information: The patient was a 48 year-old man who presented with unstable gait, frequently tripping, and occipital headache. There was no hearing loss or visual disturbance. There was no history of excessive alcohol use, drug abuse, brain surgery or trauma. He worked as an office manger in a department store and had no history of exposure to chemicals. There was no sensory or motor deficits. An MRI examination discloses a midline cerebellar mass that was 3.0 in greatest dimension. The mass filled and expanded the fourth ventricle and also involved the vermis. There was no cyst formation. The mass was isointense on T1-weighted images. Multiple small hyperintense foci consistent with "fat density" Swere present. Mild heterogeneous enhancement was also noted after gadollinium injection. The mass was isointense to focally hyperintense on T2-weighed images. Mild hydrocephalus was also present in the lateral and third ventricle. An open resection was performed. Representative histologic sections are illustrated here.
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Case of the Month Evaluation Coordinator: KarMing-Fung@ouhsc.edu