Department of Pathology, University of Oklahoma Health Sciences Center
A 30 year-old man with prolonged history of headache and a cereberbellar hemispheric mass.
Clinical information: The patient was a 30 year-old man who complained of intermittent headache for a prolonged period of time. The length of his symptoms was not certain but it was longer than 2 years. His symptoms became more constant. Shortly before that, he suffered a seizure and was admitted to the hospital. On physical examination, he neurologic examination was unremarkable and no cranial nerve manifestations were noted. The remaining part of her physical examination was within normal limits. He does not use drug. He is HIV negative and not immune compromised. The patient has no family history of genetic disease. He was a veterinary student at a local university and he had no history of contact with toxic agents. An MRI was performed and revealed a 2 cm hemispheric mass of the cerebellum. The mass was well defined and the superficial part of it appeared to have adopted to the contour of the cerebellar folia. The mass was excised and yielded the following images.
Click thumbnails
to see pictures. Panel I is stained with Luxol fast blue- Creysl Violet, Panel J
and K are immunohistochemistry for neurofilament protein (NFP), and Panel L is
immunohisochemistry for synaptophysin.
Cases of the Month Coordinator: KarMing-Fung@ouhsc.edu