Department of Pathology, University of Oklahoma Health Sciences Center

Diffuse astrocytoma (WHO II/IV)

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• Panel A: Diffuse astrocytoma has morphologic features of mature glial cells. The cellularity of these tumors are usually not high. Substantial pleomorphism and significan mitotic activity is not usually seen.

• Panel B: The bland morphology of the nuclei are best appreciated in higher mangification.

For Comment: KarMing-Fung@ouhsc.edu