Department of Pathology, University of Oklahoma Health Sciences Center

Ependymoma

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• Panel A and B are hematoxylin-eosin stained pictures that shows that perivascular arrangement of tumor cells with the characteristic hyponuclear mantle around blood vessels.
• Panel C demonstrate strong positive staining for glial fibrillary acidic protein on immunohistochemistry.
• In Panel D, minute ependymal canals are detected by immunohistochemistry for epithelial membrane antigen (EMA) which stains the luminal surface strongly.