FNA Quiz 26 A 31 year-old male inmate presented to the otorhinolaryngiology clinic with a 10 cm mass in the right side of his neck and a fine needle aspiration biopsy of the mass was performed. Regarding the disease represented by the direct smears illustrated below all of the following statements are true EXCEPT:

A The cytologic diagnosis would best be confirmed by flow cytometry.

B The presence of a granulomatous tissue reaction is not uncommon.

C Diagnostic tumor cells are more likely to be found at the periphery of the smears.

D The misinterpretation of immunoblasts for tumor cells is a common diagnostic pitfall.

E Tissue biopsy is indicated for histologic sub-typing, tumor grading, and disease prognostication.