Fluid & Brush Quiz 6 This 78 year-old white male smoker has had transitional cell carcinomas removed from his bladder twice over the last 6 years.  Both have been papillary and non-invasive.  He is being followed annually with bladder washings.  Representative photos of his latest wash are seen below.  The most probable diagnosis is:

 

 

A Benign epithelium without reactive changes.

B Benign epithelium with reactive.

C Transitional cell carcinoma, low grade and papillary.

D Transitional cell carcinoma, high grade.