Severe Infantile Weakness and Hypotonia 

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• Myopathic etiology

• Neurogenic etiology

• Non-myopathic, Non-neurogenic

• Others

Myopathic etiology Head

• Nemaline myopathy, fatal infantile onset and childhood onset type

• Myotubular myopathy, infantile onset type

• Congenital myotonic dystrophy

• Congenital muscular dystrophy, merosin deficient type

• Congenital fiber type disproportion

• Reducing body myopathy, infantile or early childhood onset type

• Glycogenosis type II, infantile variant (Pompe disease)

• Glycogenosis type VI (McArdle disease), fatal infantile form

• Glycogenosis type VII (Tarui’s disease), infantile form

• Mitochondrial-glycogen-lipid myopathy

• Lipid storage myopathy

Neuroogenic etiology Head

• Spinal muscular atrophy type I (Werdnig-Hoffmann disease)

• Spinal muscular atrophy type II  (Arrested Werdnig-Hoffmann disease)

Non-myopathic, Non-Neurogenic etiology  Head

• Ehlers-Danlos disease

• Congenital laxity of ligaments

Others  Head

• Prader-Willi syndrome