Tourette syndrome

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Summary: Tourette syndrome should not be viewed as a neurodevelopmental disorder because significant developmental delay mental retardation is usually not present. Clinical features include motor and vocal tics with onset before 18 years of age; obsessive and compulsive behavior and attention deficits hyperkinetic disorder (ADHD)

Genetics: Probably hereditary but the genetic mechanism is not clear

Clinical features: Presence of both motor and vocal tics with onset before 18 years of age. The tics can be simple (involving one muscle group) or complex (involving multiple muscle groups in a sequential movement). When the tics involve the respiratory, laryngeal, oral and nasal muscles, vocal tics will be resulted. Patients usually have obsessive and compulsive behaviors and attention deficits hyperkinetic disorder (ADHD). The personality often has intense drive, enthusiastic interests, and volatility of mood, which can be explosive and abrupt. Interestingly, some genius like Samel Johnson (compiled the first great English dictionary) and Peter the Great (Russian Tsar who started the modernization of Russia) were belived to have Tourette syndrome.

NeuroLearn NeuroHelp Neurodevelopmental Disorders  For Comment: KarMing-Fung@ouhsc.edu