NeuroSim

Teaching Cases in Neuropathology

Department of Pathology, University of Oklahoma Health Sciences Center

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Space occupying lesions of the brain and spinal cord

• A rapidly expanding mass in the posterior fossa of a 4 year-old girl. (Case 801-1)
• A 30 year-old man with prolonged history of headache and a cerebellar hemispheric mass. (Case 708-1)
• A 52 year-old man with history of endocarditis, stroke, and new enhancing lesion in temporal lobe. (Case 707-1)
• A 67 year-old woman with a cerebellar and parietal enhancing lesions. (Case 706-1)
• A 45 year-old woman with new onset seizure and an enhancing mass. (Case 705-1)
• A 33 year-old woman with a mass that extends from the frontal lobe into the nasal sinus. (Case 703-1)
• An 8 year-old boy with headache and a mass in the posterior fossa. (Case 611-1)
• An 8 year-old boy with new onset generalized seizure. (Case 609-1)
• A 10 year-old girl with a cerebral hemispheric mass and headache. (Case 606-1)
• A 75 year-old man with progressive weakness and multiple lesions in the brain. (Case 605-1)
• A 5 year-old boy with headache, vomiting, ataxia and a pineal mass. (Case 604-1)
• A 42 year-old woman with difficulties in walking, confusion, multiple white matter lesions and history of substance abuse. (Case 601-1)
• A 70 year-old man with confusion and neurologic deterioration after a minor fall. (Case 512-1)
• A 15 year-old femal with progressive myelopathy (Case P-03).
• A 28 year-old woman with a pineal mass. (Case 505-1)
• An 18 month-old girl with a hypothalamic mass. (Case 503-1)
• A 65 year-old woman with an intraventricular mass. (Case 501-2)
• A 12 year-old girl with an enlarged optic nerve. (Case 412-1)
• A 48 year-old man with a midline cerebellar mass. (Case 411-4)
• A 40 year-old man with back pain and a sacral mass. (Case 411-3)
• A 2 year-old girl with a funny looking eye. (Case 411-2)
• A 23 year-old woman with elevated serum creatine kinase level and muscle weakness. (Case 411-1)
• A 5 month-old boy with a superficially located, partially cystic hemispheric mass. (Case 406-1)
• A large cerebellar mass (Case 403-2)
• A 28 year-old woman with headache and visual disturbance (Case 312-1)
• A 5 year-old boy with nausea and vomiting for 3 months (Case 401-2)
• A 45 year-old woman with a sellar mass (Case 403-1)
• A 20 year-old man with a sellar-suprasellar mass and sudden loss of vision (Sim04)
• A 21 year-old woman who rapidly becomes quadriplegic (Sim02)
• A 10 year-old girl with a hemispheric mass and hydrocephalus (Sim03)
• A 18 year-old man with headache, ataxia, and cerebellar mass (Case 404-2)
• A 45 year-old woman with an enhancing brain mass (Case 306-1)
• A 32 year-old woman with a ventricular tumor. (Case 307-1)
• A 55 year-old man with an enhancing parietal mass (Case 311-1) 
• A 5 year-old boy with a cystic lesion in the filum terminale (Case 309-2)

Cranial and vertebral lesions

• A 37 year-old man with a bone eroding mass in the cervical spine. (Case 612-1)
• A 25 year-old woman with vertebral/paravertebral mass at the thoracic spine (Case 304-2)
• A 29 year-old woman with a skull mass for two months (Case P-02)
• A 13 year-old girl with a mass in temporal bone (Case 402-2)

Non-space occupying lesions of the central nervous system

• A 10 year-old boy with history of asthma and lower extremity weakness. (Case 501-1)
• A 70 year-old man with rigidity, decreased ocular movements, and dementia (Case P-01)
• A 54 year-old man with acute onset pain, delusion, and rapid deterioration. (Case 308-1)
• A 10 year-old boy with history of asthma and lower extremity weakness. (Case 501-1)
• An unresponsive 55 year-old woman. (Case 504-1)
• A 10 year-old boy with headache, rapid neurologic deterioration, leptomeningeal and parenchymal enhancement. (Case 511-1)

Muscle and nerve biopsy

• A 56 year-old woman with rash and generalized weakness (Case 310-1)
• A 5 year-old girl with muscle weakness and pain (Case 305-2)
• A 52 year-old man with muscle weakness (Case 404-1)
• A 60 year-old man with lower limb weakness, pain, and numbness (Sim01)

• A full term neonate with severe hypotonia (Sim06)

• A 56 year-old man with muscle pain and progressive muscle weakness (Case 401-3)

• A 23 year-old woman with elevated serum creatine kinase level and muscle weakness. (Case 411-1)