Department of Pathology, University of Oklahoma Health Sciences Center

NeuroTest Sample Question #38 Next question Previous question

Answer: C (This picture is taken from the cerebellum and the structure is a heterotopia) Level of difficulty: 3 NeuroTest NeuroLearn NeuroHelp

Discussion: 

• Part of the cerebellar folia are included in this photograph (Þ). Part of a cerebellar nuclei, most likely the dentate nucleus, is also present in the other corner (ß). If you compare the histology of the round structure with the cerebellar cortex,  it appeared at this level that it is composed of disorganized tissue that has feature of the cerebellar folia. Specifically, features of the internal granular layer and the molecular layer. This magnification is too low for recognition of the Purkinje cells. The morphologic features of the heterotopuic cells may vary from primitive appear cells reminiscent of the primitive neuroepithelial cells to well developed and mature but disorganized tissue with features of the internal granular layer, Purkinje cells, and cerebellar molecular layer as illustrated in this case. 

 Comment: KarMing-Fung@ouhsc.edu