The pathologic changes indicated by the arrow:

1. Can be demonstrated by Gallya stain and Bielschowsky stain.

2. Can be demonstrated by thioflavin-S stain.

3. Can be demonstrated by immunohistochemistry for tau protein.

4. Can be demonstrated by immunohistochemistry for alpha-synuclein.

A. I, 2, and 3 are true.

B. Only 1 and 3 are true.

C. Only 2 and 4 are true.

D. Only 4 is true.

E. None of the above.

Answer and Discussion

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