11/21/2006, Tuesday, Noon

Neurology Grand Round

Vose Auditorium, Presbyterian Tower

Unknown Conference at 9:00 a.m., Everett Tower 3B Multiheaded Scope Room

2

03/05/2007, Monday, Noon

Pathology Grand Round

Hensley Library, BMSB 4th floor

Unknown Conference at 9:00 a.m., Everett Tower 3B Multiheaded Scope Room

Kevin Raymond, M.D., Department of Anatomic Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas

Bone tumors in neuropathology

5/6/2008, Tuesday, 8:00

Neurology Grand Round

Neurology Library

Unknown Conference: Immediately after Grand Round in Neurology Library, Presbyterian Professional Building

4

Postpone, that new date will be announced later.

2006-2007

Introduction to Neuropathology

Learning Objectives:

·          Birds eye view on the type of neuropathologic process.

·          Introduction to histologic techniques in neuropathology.

·          Capsule review on developmental, macroscopic, and microscopic anatomy.

Learning Objectives:

·          Pathology of blunt (closed cranial) trauma.

·          Pathology of penetrating (low velocity and high velocity) trauma.

·          Pathology of shaken-impact baby syndrome and child abuse.

Learning Objectives:

·          Introduction to the types of myopathic processes.

·          Review of histochemical techniques.

·          Review on structure of the peripheral nervous system.

·          Pathology of inflammatory myopathies.

Learning Objectives:

·          Introduction to the classification of brain tumors.

·          Brief review of specialized techniques including FISH.

·          Brief discussion on the WHO classification.

Learning Objectives:

·          Understand dystrophinopathies and other dystrophies.

·          Understand x-linked myotubular myopathy, centronuclear myopathy, and central core disease.

·          Understand mitochondrial myopathies (MELAS) and glycogen storage diseases (McArdle disease).

Learning Objectives:

·          Understand the diagnostic criteria and shared properties of CNS tumors with embryonal features.

·          Understand the different types of rosettes.

·          Understand the molecular pathology techniques that are used in embryonal tumors.

Learning Objectives:

·          Understand the WHO classifications on glial tumors.

·          Understand the diagnostic criteria on astrocytic, oligodendroglial, ependymal, and mixed tumors.

·          Understand the molecular mechanism of tumor progression and their impact on diagnosis and therapy.

Learning Objectives:

·          Brief review on developmental anatomy.

·          Learn to correlate pathologic changes with developmental milestones.

·          Understand the pathology of periventricular (germinal matrix) hemorrhage and periventricular leukoencephalopathy (PVL).

·          Understand the pathology of perinatal ischemic hypoxic injuries.

Learning Objectives:

·          Understand the pathologic mechanisms and diagnostic of demyelinating diseases and the special features of “variation on the same theme” in different demyelinating diseases.

·          Be familiar on the special staining techniques required for the diagnosis of demyelinating diseases.

·          Learn the pathology of central pontine myelinolysis.

Learning Objectives:

·          Understand the WHO classification on neuronal and  and glial-neuronal tumor.

·          Understand the spectrum of this family that goes from pure neuronal to glial-neuronal phenotypes.

·          Familiar with the diagnostic criteria of common glial-neuronal tumors.

·          Understand the relationship between these tumors and cortical dysplasia.

Learning Objectives:

·          Learn the pathology of common infections and the morphology of some parasites.

·          Understand the use of special stain and molecular biology techniques in the diagnosis of CNS infections.

·          Understand the limitation in the use of microscope in the diagnosis of infection.

Learning Objectives:

·          Review on several common non-neoplastic pathologic entities that mimic genuine neoplasms.

·          Review on several tumors that histologically mimic a non-neoplastic process.

Learning Objectives:

·          Understand the variety of diseases that are caused by viruses and their relation to the immune status of the host.

·          Be familiar with the molecular biology technique and special stain for the diagnosis of viral and fungal infections.

·          Learn the pathology of Rasmussen’s encephalitis.

2007-2008

Learning Objectives:

·          Birds eye view on the type of neuropathologic process.

·          Introduction to histologic techniques in neuropathology.

·          Capsule review on developmental, macroscopic, and microscopic anatomy.

Learning Objectives:

·          Brief review on the pathologic mechanism of metabolic diseases particularly peroxisomal, lysosomal, and mitochondrial diseases.

·          Understand the shared macroscophic and histologic features of different leukodystrophies.

Learning Objectives:

·          Understand the WHO classification on meningiomas.

·          Understand the diagnostic criteria for meningioma, atypical meningioima, and malignant (anaplastic) meningioma.

·          Learn the molecular mechanism in the progression of meningiomas.

·          Learn the differential diagnoses of meiningiomas.

·          Review on the features of mesenchymal tumors arising around within and around the CNS.

Learning Objectives:

·          Review on embryonal development of the CNS.

·          Understand the pathology of neurotube defects.

·          Understand the pathology of midline defects around the central nervous system and also their relationship with the developing CNS and its surrounding organs.

Learning Objectives:

·          Understand the basic pattern of macroscopic pattern formation of the brain.

·          Learn the concept of migration disorder.

·          Review on the common malformations of the cerebral hemispheres.

Learning Objectives:

·          Learn the pathology of choroid plexus tumors, germ cell tumors, lymphoma, and craniopharyngioma.

·          Understand the pathologic mechanisms of metastases to the CNS and the guideline in differentiating the source of origin.

Learning Objectives:

·          Review on the architecture of the limbic system.

·          Review in the overall concept of neurodegenerative diseases.

·          Understand the pathologic features of common dementia including Alzheimer’s disease, dementia with Lewy bodies, and Pick’s disease.

Learning Objectives:

·          Learn the pathology of pituitary adenomas and other primary tumors, cysts, and inflammatory lesions of the pituitary glands and sellar region.

Learning Objectives:

·          Review on pathology of ischemic/hypoxic injuries in infants and adults.

·          Understand the differences between infants and adults on hypoxic/ischemic injury.

·          Learn the pathologic features of infantile and perinatal hypoxic/ischemic injury and atherosclerosis.

·          Learn the pathologic features of stroke, carbon monoxide poisoning, MELAS, stroke and infarction, hypotension and circulatory arrest.

Learning Objectives:

·          Learn the shared pathology and mechanism of movement disorder.

·          Learn the pathology and diagnostic criteria of Parkinson’s disease, progressive pseudonuclear palsy, cortical basal degeneration and others.

Learning Objectives:

·          Compare and contrast the pathology of vasculitis and vasculopathy.

·          Learn the pathologic features of common vasculitis and vasculopathies including primary angiitis of the CNS, CADASIL, and cerebral amyloid angiopathy.

Learning Objectives:

·          Learn the pathology of aneurysm, vascular malformation of the brain and spinal cord, and ectomesodermal syndrome associated with vascular malformation.

Learning Objectives:

·          Learn the pathology of Prion diseases.

·          Learn the pathology of selected degenerative diseases including Wilson’s disease, hepatoencephalopathy, and neuroaxonal degeneration.